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Structural and Functional Analysis of the CspB Protease Required for Clostridium Spore Germination

Spores are the major transmissive form of the nosocomial pathogen Clostridium difficile, a leading cause of healthcare-associated diarrhea worldwide. Successful transmission of C. difficile requires that its hardy, resistant spores germinate into vegetative cells in the gastrointestinal tract. A cri...

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Detalles Bibliográficos
Autores principales: Adams, Chloe M., Eckenroth, Brian E., Putnam, Emily E., Doublié, Sylvie, Shen, Aimee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567191/
https://www.ncbi.nlm.nih.gov/pubmed/23408892
http://dx.doi.org/10.1371/journal.ppat.1003165