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A novel F(420)-dependent anti-oxidant mechanism protects Mycobacterium tuberculosis against oxidative stress and bactericidal agents

Mycobacterium tuberculosis (Mtb) is an aerobic bacterium that persists intracellularly in host macrophages and has evolved diverse mechanisms to combat and survive oxidative stress. Here we show a novel F(420)-dependent anti-oxidant mechanism that protects Mtb against oxidative stress. Inactivation...

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Detalles Bibliográficos
Autores principales: Gurumurthy, Meera, Rao, Martin, Mukherjee, Tathagata, Rao, Srinivasa P S, Boshoff, Helena I, Dick, Thomas, Barry, Clifton E, Manjunatha, Ujjini H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567243/
https://www.ncbi.nlm.nih.gov/pubmed/23240649
http://dx.doi.org/10.1111/mmi.12127