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Cancer stem cells as ‘units of selection’
Cancer development is widely recognized to be a somatic cell evolutionary process with complex dynamics and highly variable time frames. Variant cells and descendent subclones gain competitive advantage via their fitness in relation to micro-environmental selective pressures. In this context, the ‘u...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Blackwell Publishing Ltd
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567475/ https://www.ncbi.nlm.nih.gov/pubmed/23396760 http://dx.doi.org/10.1111/eva.12017 |