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Copy number gain of MYCN gene is a recurrent genetic aberration and favorable prognostic factor in Chinese pediatric neuroblastoma patients

BACKGROUND: Amplification of MYCN oncogene is an established marker indicating aggressive tumor progression of neuroblastoma (NBL). But copy number analyses of MYCN gene in ganglioneuroblastoma (GNBL) and ganglioneuroma(GN) is poorly described in the literature. In the study, we evaluated the copy n...

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Detalles Bibliográficos
Autores principales: Wang, Miao, Zhou, Chunju, Cai, Rongqin, Li, Yong, Gong, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567989/
https://www.ncbi.nlm.nih.gov/pubmed/23320395
http://dx.doi.org/10.1186/1746-1596-8-5