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The Wilms’ tumor gene (WT1) regulates E-cadherin expression and migration of prostate cancer cells

BACKGROUND: One key step in the development of prostate cancer (PCa) metastasis is the loss of E-cadherin expression associated with increased cellular motility and tumor invasion. This loss of E-cadherin expression is also required during normal embryogenesis and similar transcriptional repressors...

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Detalles Bibliográficos
Autores principales: Brett, Adina, Pandey, Sony, Fraizer, Gail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568020/
https://www.ncbi.nlm.nih.gov/pubmed/23298185
http://dx.doi.org/10.1186/1476-4598-12-3