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The evolution of antibiotic susceptibility and resistance during the formation of Escherichia coli biofilms in the absence of antibiotics

BACKGROUND: Explanations for bacterial biofilm persistence during antibiotic treatment typically depend on non-genetic mechanisms, and rarely consider the contribution of evolutionary processes. RESULTS: Using Escherichia coli biofilms, we demonstrate that heritable variation for broad-spectrum anti...

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Detalles Bibliográficos
Autores principales: Tyerman, Jabus G, Ponciano, José M, Joyce, Paul, Forney, Larry J, Harmon, Luke J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568021/
https://www.ncbi.nlm.nih.gov/pubmed/23356665
http://dx.doi.org/10.1186/1471-2148-13-22