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A Novel Mechanism of PPAR Gamma Induction via EGFR Signalling Constitutes Rational for Combination Therapy in Bladder Cancer

BACKGROUND: Two signalling molecules that are attractive for targeted therapy are the epidermal growth factor receptor (EGFR) and the peroxisome proliferator-activated receptor gamma (PPARγ). We investigated possible crosstalk between these 2 pathways, particularly in light of the recent evidence im...

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Detalles Bibliográficos
Autores principales: Mansure, Jose Joao, Nassim, Roland, Chevalier, Simone, Szymanski, Konrad, Rocha, Joice, Aldousari, Saad, Kassouf, Wassim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568080/
https://www.ncbi.nlm.nih.gov/pubmed/23409107
http://dx.doi.org/10.1371/journal.pone.0055997