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A Novel Mechanism of PPAR Gamma Induction via EGFR Signalling Constitutes Rational for Combination Therapy in Bladder Cancer
BACKGROUND: Two signalling molecules that are attractive for targeted therapy are the epidermal growth factor receptor (EGFR) and the peroxisome proliferator-activated receptor gamma (PPARγ). We investigated possible crosstalk between these 2 pathways, particularly in light of the recent evidence im...
Autores principales: | Mansure, Jose Joao, Nassim, Roland, Chevalier, Simone, Szymanski, Konrad, Rocha, Joice, Aldousari, Saad, Kassouf, Wassim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568080/ https://www.ncbi.nlm.nih.gov/pubmed/23409107 http://dx.doi.org/10.1371/journal.pone.0055997 |
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