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Sustained Delivery of IL-1Ra from PF127-Gel Reduces Hyperglycemia in Diabetic GK-Rats

Interleukin-1beta (IL-1β) is a major cause for induction of various inflammatory mechanisms that are decisively involved to provoke pathogenesis of type 2 diabetes mellitus (T2DM). Interleukin-1 receptor antagonist (IL-1Ra) a naturally occurring anti-inflammatory antagonist of IL-1β has been recentl...

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Detalles Bibliográficos
Autores principales: Akash, Muhammad Sajid Hamid, Rehman, Kanwal, Sun, Hongying, Chen, Shuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568082/
https://www.ncbi.nlm.nih.gov/pubmed/23409091
http://dx.doi.org/10.1371/journal.pone.0055925