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DNA Methylation Analysis in the Intestinal Epithelium—Effect of Cell Separation on Gene Expression and Methylation Profile

BACKGROUND: Epigenetic signatures are highly cell type specific. Separation of distinct cell populations is therefore desirable for all epigenetic studies. However, to date little information is available on whether separation protocols might influence epigenetic and/or gene expression signatures an...

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Detalles Bibliográficos
Autores principales: Jenke, Andreas C., Postberg, Jan, Raine, Timothy, Nayak, Komal M., Molitor, Malte, Wirth, Stefan, Kaser, Arthur, Parkes, Miles, Heuschkel, Robert B., Orth, Valerie, Zilbauer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568120/
https://www.ncbi.nlm.nih.gov/pubmed/23409010
http://dx.doi.org/10.1371/journal.pone.0055636