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Therapeutic Targeting of Lewis(y) and Lewis(b) with a Novel Monoclonal Antibody 692/29
BACKGROUND: Several monoclonal antibodies (mAbs) recognising Lewis(y), such as BR96, have reached the clinic but have failed to show good anti-tumour responses with an acceptable level of toxicity. No Lewis(b) mAbs have been trialled in patients. In this study we compare the specificity of three mAb...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568143/ https://www.ncbi.nlm.nih.gov/pubmed/23408949 http://dx.doi.org/10.1371/journal.pone.0054892 |