Oncodrive-CIS: A Method to Reveal Likely Driver Genes Based on the Impact of Their Copy Number Changes on Expression

A well-established approach for detecting genes involved in tumorigenesis due to copy number alterations (CNAs) is to assess the recurrence of the alteration across multiple samples. Expression data can be used to filter this list of candidates by assessing whether the gene expression significantly...

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Detalles Bibliográficos
Autores principales: Tamborero, David, Lopez-Bigas, Nuria, Gonzalez-Perez, Abel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568145/
https://www.ncbi.nlm.nih.gov/pubmed/23408991
http://dx.doi.org/10.1371/journal.pone.0055489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568145/
https://www.ncbi.nlm.nih.gov/pubmed/23408991
http://dx.doi.org/10.1371/journal.pone.0055489

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