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Multi-Species Comparative Analysis of the Equine ACE Gene Identifies a Highly Conserved Potential Transcription Factor Binding Site in Intron 16

Angiotensin converting enzyme (ACE) is essential for control of blood pressure. The human ACE gene contains an intronic Alu indel (I/D) polymorphism that has been associated with variation in serum enzyme levels, although the functional mechanism has not been identified. The polymorphism has also be...

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Detalles Bibliográficos
Autores principales: Hamilton, Natasha A., Tammen, Imke, Raadsma, Herman W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568152/
https://www.ncbi.nlm.nih.gov/pubmed/23408978
http://dx.doi.org/10.1371/journal.pone.0055434