The Programming of Cardiac Hypertrophy in the Offspring by Maternal Obesity Is Associated with Hyperinsulinemia, AKT, ERK, and mTOR Activation

Human and animal studies suggest that suboptimal early nutrition during critical developmental periods impacts long-term health. For example, maternal overnutrition during pregnancy and lactation in mice programs insulin resistance, obesity, and endothelial dysfunction in the offspring. Here we inve...

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Detalles Bibliográficos
Autores principales: Fernandez-Twinn, Denise S., Blackmore, Heather L., Siggens, Lee, Giussani, Dino A., Cross, Christine M., Foo, Roger, Ozanne, Susan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2012
Materias:
Renal-Cardiac-Vascular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568261/
https://www.ncbi.nlm.nih.gov/pubmed/23070543
http://dx.doi.org/10.1210/en.2012-1508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568261/
https://www.ncbi.nlm.nih.gov/pubmed/23070543
http://dx.doi.org/10.1210/en.2012-1508

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