Timothy Syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons

L-type voltage gated calcium channels (LTCs) play an important role in neuronal development by promoting dendritic growth and arborization(1–3). A point mutation in Ca(V)1.2 causes Timothy Syndrome (TS)(4), a neurodevelopmental disorder associated with autism spectrum disorders (ASD). We report that...

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Detalles Bibliográficos
Autores principales: Krey, Jocelyn F., Pasca, Sergiu P., Shcheglovitov, Aleksandr, Yazawa, Masayuki, Schwemberger, Rachel, Rasmusson, Randall, Dolmetsch, Ricardo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568452/
https://www.ncbi.nlm.nih.gov/pubmed/23313911
http://dx.doi.org/10.1038/nn.3307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568452/
https://www.ncbi.nlm.nih.gov/pubmed/23313911
http://dx.doi.org/10.1038/nn.3307

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