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Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history

The genes involved in host defences are known to undergo rapid evolution. Therefore, it is often difficult to assign orthologs in multigene families among various vertebrate species. Chemokines are a large family of small cytokines that orchestrate cell migration in health and disease. Herein, we ha...

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Detalles Bibliográficos
Autores principales: Nomiyama, Hisayuki, Osada, Naoki, Yoshie, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568907/
https://www.ncbi.nlm.nih.gov/pubmed/23145839
http://dx.doi.org/10.1111/gtc.12013