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P2X7 Receptor Activation Induces Reactive Oxygen Species Formation and Cell Death in Murine EOC13 Microglia

The P2X7 purinergic receptor is a ligand-gated cation channel expressed on leukocytes including microglia. This study aimed to determine if P2X7 activation induces the uptake of organic cations, reactive oxygen species (ROS) formation, and death in the murine microglial EOC13 cell line. Using the mu...

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Detalles Bibliográficos
Autores principales: Bartlett, Rachael, Yerbury, Justin J., Sluyter, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568910/
https://www.ncbi.nlm.nih.gov/pubmed/23431238
http://dx.doi.org/10.1155/2013/271813