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Spike-Driven Glutamate Electrodiffusion Triggers Synaptic Potentiation via a Homer-Dependent mGluR-NMDAR Link
Electric fields of synaptic currents can influence diffusion of charged neurotransmitters, such as glutamate, in the synaptic cleft. However, this phenomenon has hitherto been detected only through sustained depolarization of large principal neurons, and its adaptive significance remains unknown. He...
Autores principales: | Sylantyev, Sergiy, Savtchenko, Leonid P., Ermolyuk, Yaroslav, Michaluk, Piotr, Rusakov, Dmitri A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568920/ https://www.ncbi.nlm.nih.gov/pubmed/23395378 http://dx.doi.org/10.1016/j.neuron.2012.11.026 |
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