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Design and physicochemical characterization of advanced spray-dried tacrolimus multifunctional particles for inhalation

The aim of this study was to design, develop, and optimize respirable tacrolimus microparticles and nanoparticles and multifunctional tacrolimus lung surfactant mimic particles for targeted dry powder inhalation delivery as a pulmonary nanomedicine. Particles were rationally designed and produced at...

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Detalles Bibliográficos
Autores principales: Wu, Xiao, Hayes, Don, Zwischenberger, Joseph B, Kuhn, Robert J, Mansour, Heidi M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569053/
https://www.ncbi.nlm.nih.gov/pubmed/23403805
http://dx.doi.org/10.2147/DDDT.S40166