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In Vivo Evaluation of (11)C-labeled Three Radioligands for Glycine Transporter 1 in the Mouse Brain

OBJECTIVE: Glycine transporter 1 (GlyT-1) is one of the most attractive therapeutic targets for schizophrenia. There is great interest in developing radioligands for in vivo imaging of GlyT-1 in the brain using positron emission tomography. Here, we report the properties of three novel non-sarcosine...

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Detalles Bibliográficos
Autores principales: Zhang, Ji-chun, Toyohara, Jun, Wu, Jin, Ishiwata, Kiichi, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Neuropsychopharmacology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569154/
https://www.ncbi.nlm.nih.gov/pubmed/23429671
http://dx.doi.org/10.9758/cpn.2012.10.1.34