Iptakalim Preferentially Decreases Nicotine-induced Hyperlocomotion in Phencyclidine-sensitized Rats: A Potential Dual Action against Nicotine Addiction and Psychosis

OBJECTIVE: Iptakalim is a putative ATP-sensitive potassium (K(ATP)) channel opener. It is also a novel nicotinic acetylcholine receptor (nAChR) blocker and can antagonize nicotine-induced increase in dopamine release in the nucleus accumbens. Our recent work also shows that iptakalim exhibits a cloz...

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Detalles Bibliográficos
Autores principales: Volf, Nick, Hu, Gang, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Neuropsychopharmacology 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569163/
https://www.ncbi.nlm.nih.gov/pubmed/23430396
http://dx.doi.org/10.9758/cpn.2012.10.3.168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569163/
https://www.ncbi.nlm.nih.gov/pubmed/23430396
http://dx.doi.org/10.9758/cpn.2012.10.3.168

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