Expression of TP53 Isoforms p53β or p53γ Enhances Chemosensitivity in TP53(null) Cell Lines

The carboxy-terminal truncated p53 alternative spliced isoforms, p53β and p53γ, are expressed at disparate levels in cancer and are suggested to influence treatment response and therapy outcome. However, their functional role in cancer remains to be elucidated. We investigated their individual funct...

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Detalles Bibliográficos
Autores principales: Silden, Elisabeth, Hjelle, Sigrun M., Wergeland, Line, Sulen, André, Andresen, Vibeke, Bourdon, Jean-Christophe, Micklem, David R., McCormack, Emmet, Gjertsen, Bjørn Tore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569410/
https://www.ncbi.nlm.nih.gov/pubmed/23409163
http://dx.doi.org/10.1371/journal.pone.0056276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569410/
https://www.ncbi.nlm.nih.gov/pubmed/23409163
http://dx.doi.org/10.1371/journal.pone.0056276

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