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Expression of TP53 Isoforms p53β or p53γ Enhances Chemosensitivity in TP53(null) Cell Lines
The carboxy-terminal truncated p53 alternative spliced isoforms, p53β and p53γ, are expressed at disparate levels in cancer and are suggested to influence treatment response and therapy outcome. However, their functional role in cancer remains to be elucidated. We investigated their individual funct...
Autores principales: | Silden, Elisabeth, Hjelle, Sigrun M., Wergeland, Line, Sulen, André, Andresen, Vibeke, Bourdon, Jean-Christophe, Micklem, David R., McCormack, Emmet, Gjertsen, Bjørn Tore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569410/ https://www.ncbi.nlm.nih.gov/pubmed/23409163 http://dx.doi.org/10.1371/journal.pone.0056276 |
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