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Novel Gene Therapy Viral Vector Using Non-Oncogenic Lymphotropic Herpesvirus

Despite the use of retroviral vectors, efficiently introducing target genes into immunocytes such as T cells is difficult. In addition, retroviral vectors carry risks associated with the oncogenicity of the native virus and the potential for introducing malignancy in recipients due to genetic carryo...

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Detalles Bibliográficos
Autores principales: Shimizu, Akihiro, Kobayashi, Nobuyuki, Shimada, Kazuya, Oura, Kuniaki, Tanaka, Tadao, Okamoto, Aikou, Kondo, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569415/
https://www.ncbi.nlm.nih.gov/pubmed/23409116
http://dx.doi.org/10.1371/journal.pone.0056027