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Novel Gene Therapy Viral Vector Using Non-Oncogenic Lymphotropic Herpesvirus
Despite the use of retroviral vectors, efficiently introducing target genes into immunocytes such as T cells is difficult. In addition, retroviral vectors carry risks associated with the oncogenicity of the native virus and the potential for introducing malignancy in recipients due to genetic carryo...
Autores principales: | Shimizu, Akihiro, Kobayashi, Nobuyuki, Shimada, Kazuya, Oura, Kuniaki, Tanaka, Tadao, Okamoto, Aikou, Kondo, Kazuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569415/ https://www.ncbi.nlm.nih.gov/pubmed/23409116 http://dx.doi.org/10.1371/journal.pone.0056027 |
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