Intravitreal Administration of HA-1077, a ROCK Inhibitor, Improves Retinal Function in a Mouse Model of Huntington Disease

Huntington disease (HD) is an inherited neurodegenerative disease that affects multiple brain regions. It is caused by an expanded polyglutamine tract in huntingtin (Htt). The development of therapies for HD and other neurodegenerative diseases has been hampered by multiple factors, including the la...

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Detalles Bibliográficos
Autores principales: Li, Mei, Yasumura, Douglas, Ma, Aye Aye K., Matthes, Michael T., Yang, Haidong, Nielson, Gregory, Huang, Yong, Szoka, Francis C., LaVail, Matthew M., Diamond, Marc I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569418/
https://www.ncbi.nlm.nih.gov/pubmed/23409115
http://dx.doi.org/10.1371/journal.pone.0056026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569418/
https://www.ncbi.nlm.nih.gov/pubmed/23409115
http://dx.doi.org/10.1371/journal.pone.0056026

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