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Foxp3(+) Treg Expanded from Patients with Established Diabetes Reduce Helios Expression while Retaining Normal Function Compared to Healthy Individuals

Foxp3(+) regulatory T cells (Treg) play a crucial role in regulating immune tolerance. The use of Treg to restore immune tolerance is considered an attractive novel approach to inhibit autoimmune disease, including type 1 diabetes (T1D), and to prevent rejection of organ transplants. In view of the...

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Detalles Bibliográficos
Autores principales: Du, Weiting, Shen, Yueh-Wei, Lee, Wen-Hui, Wang, Ding, Paz, Sachiko, Kandeel, Fouad, Liu, Chih-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569420/
https://www.ncbi.nlm.nih.gov/pubmed/23409157
http://dx.doi.org/10.1371/journal.pone.0056209