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DNA-Fragments Are Transcytosed across CaCo-2 Cells by Adsorptive Endocytosis and Vesicular Mediated Transport

Dietary DNA is degraded into shorter DNA-fragments and single nucleosides in the gastrointestinal tract. Dietary DNA is mainly taken up as single nucleosides and bases, but even dietary DNA-fragments of up to a few hundred bp are able to cross the intestinal barrier and enter the blood stream. The m...

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Detalles Bibliográficos
Autores principales: Johannessen, Lene E., Spilsberg, Bjørn, Wiik-Nielsen, Christer R., Kristoffersen, Anja B., Holst-Jensen, Arne, Berdal, Knut G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569430/
https://www.ncbi.nlm.nih.gov/pubmed/23409196
http://dx.doi.org/10.1371/journal.pone.0056671