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Toll-Like Receptor 4 Engagement Drives Differentiation of Human and Murine Dendritic Cells from a Pro- into an Anti-Inflammatory Mode

The dendritic cell (DC) coordinates innate and adaptive immunity to fight infections and cancer. Our observations reveal that DCs exposed to the microbial danger signal lipopolysaccharide (LPS) in the presence of interferon-γ (IFN-γ) acquire a continuously changing activation/maturation phenotype. T...

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Detalles Bibliográficos
Autores principales: Luger, Romana, Valookaran, Sneha, Knapp, Natalie, Vizzardelli, Caterina, Dohnal, Alexander M., Felzmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569454/
https://www.ncbi.nlm.nih.gov/pubmed/23408948
http://dx.doi.org/10.1371/journal.pone.0054879