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The Pathogenic Aβ43 Is Enriched in Familial and Sporadic Alzheimer Disease
The amyloid-cascade hypothesis posits that the role of amyloid β-peptide (Aβ) in Alzheimer disease (AD) involves polymerization into structures that eventually are deposited as amyloid plaques. During this process, neurotoxic oligomers are formed that induce synaptic loss and neuronal death. Several...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569467/ https://www.ncbi.nlm.nih.gov/pubmed/23409063 http://dx.doi.org/10.1371/journal.pone.0055847 |