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One-pot efficient synthesis of N(α)-urethane-protected β- and γ-amino acids
1-[(4-Methylphenyl)oxy]pyrrolidine-2,5-dione and 1-[(4-methylphenyl)oxy]piperidine-2,6-dione react in a Lossen-type reaction with primary alcohols in the presence of triethylamine to furnish corresponding N (α)-urethane-protected β-alanine and γ-aminopropionic acid (GABA), respectively, with excelle...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569585/ https://www.ncbi.nlm.nih.gov/pubmed/23250684 http://dx.doi.org/10.1007/s00726-012-1443-3 |