Cargando…

The Discovery of Dabigatran Etexilate

Thromboembolic disease is a major cause of mortality and morbidity in the developed world and is caused by an excessive stimulation of coagulation. Thrombin is a key serine protease in the coagulation cascade and numerous efforts have been made to develop safe and effective orally active direct thro...

Descripción completa

Detalles Bibliográficos
Autores principales: van Ryn, Joanne, Goss, Ashley, Hauel, Norbert, Wienen, Wolfgang, Priepke, Henning, Nar, Herbert, Clemens, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569592/
https://www.ncbi.nlm.nih.gov/pubmed/23408233
http://dx.doi.org/10.3389/fphar.2013.00012