Tumor-specific CD4(+) T cells develop cytotoxic activity and eliminate virus-induced tumor cells in the absence of regulatory T cells

The important role of tumor-specific cytotoxic CD8(+) T cells is well defined in the immune control of the tumors, but the role of effector CD4(+) T cells is poorly understood. In the current research, we have used a murine retrovirus-induced tumor cell line of C57BL/6 mouse origin, namely FBL-3 cel...

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Detalles Bibliográficos
Autores principales: Akhmetzyanova, Ilseyar, Zelinskyy, Gennadiy, Schimmer, Simone, Brandau, Sven, Altenhoff, Petra, Sparwasser, Tim, Dittmer, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569596/
https://www.ncbi.nlm.nih.gov/pubmed/22890822
http://dx.doi.org/10.1007/s00262-012-1329-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569596/
https://www.ncbi.nlm.nih.gov/pubmed/22890822
http://dx.doi.org/10.1007/s00262-012-1329-y

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