Insight towards the conserved water mediated recognition of catalytic and structural Zn(+2) ions in human Matrix Metalloproteinase-8 enzyme: A study by MD-simulation methods

Human matrix metalloproteinase-8 (hMMP-8) plays a important role in the progression of colorectal cancer, metastasis, multiple sclerosis and rheumetoid arthritis. Extensive MD-simulation of the PDB and solvated structures of hMMP-8 has revealed the presence of few conserved water molecules around th...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Bornali, Bairagya, Hridoy R, Mishra, Deepak Kr, Chatterjee, Pradip Kumar, Mukhopadhyay, Bishnu P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2013
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569599/
https://www.ncbi.nlm.nih.gov/pubmed/23423544
http://dx.doi.org/10.6026/97320630009126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569599/
https://www.ncbi.nlm.nih.gov/pubmed/23423544
http://dx.doi.org/10.6026/97320630009126

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