Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

Two motor neuron diseases, amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), are caused by distinct genes involved in RNA metabolism, TDP-43 and FUS/TLS, and SMN, respectively. However, whether there is a shared defective mechanism in RNA metabolism common to these two diseases...

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Detalles Bibliográficos
Autores principales: Tsuiji, Hitomi, Iguchi, Yohei, Furuya, Asako, Kataoka, Ayane, Hatsuta, Hiroyuki, Atsuta, Naoki, Tanaka, Fumiaki, Hashizume, Yoshio, Akatsu, Hiroyasu, Murayama, Shigeo, Sobue, Gen, Yamanaka, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569639/
https://www.ncbi.nlm.nih.gov/pubmed/23255347
http://dx.doi.org/10.1002/emmm.201202303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569639/
https://www.ncbi.nlm.nih.gov/pubmed/23255347
http://dx.doi.org/10.1002/emmm.201202303

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