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Skin-draining lymph node priming is sufficient to induce sterile immunity against pre-erythrocytic malaria

The Plasmodium-infected hepatocyte has been considered necessary to prime the immune responses leading to sterile protection after vaccination with attenuated sporozoites. However, it has recently been demonstrated that priming also occurs in the skin. We wished to establish if sterile protection co...

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Detalles Bibliográficos
Autores principales: Obeid, Michel, Franetich, Jean-François, Lorthiois, Audrey, Gego, Audrey, Grüner, Anne Charlotte, Tefit, Maurel, Boucheix, Claude, Snounou, Georges, Mazier, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569641/
https://www.ncbi.nlm.nih.gov/pubmed/23255300
http://dx.doi.org/10.1002/emmm.201201677