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Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3-only proteins Bim and Bmf

Anti-apoptotic Bcl-2 family members are critical for the regulation of haematopoietic stem and progenitor cell (HSPC) survival. Little is known about the role of their pro-apoptotic antagonists, i.e. ‘BH3-only’ proteins, in this cell compartment. Based on the analysis of cytokine deprivation-induced...

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Detalles Bibliográficos
Autores principales: Labi, Verena, Bertele, Daniela, Woess, Claudia, Tischner, Denise, Bock, Florian J, Schwemmers, Sven, Pahl, Heike L, Geley, Stephan, Kunze, Mirjam, Niemeyer, Charlotte M, Villunger, Andreas, Erlacher, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569658/
https://www.ncbi.nlm.nih.gov/pubmed/23180554
http://dx.doi.org/10.1002/emmm.201201235