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Exploring the effects of polymorphisms on cis-regulatory signal transduction response

cis-Regulatory sequences (CRSs) direct cell-specific and inducible gene expression in response to signal transduction networks, and it is becoming apparent that many cases of disease susceptibility and drug response stratification are due to polymorphisms that alter CRS responses in a context-depend...

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Detalles Bibliográficos
Autores principales: MacKenzie, Alasdair, Hing, Benjamin, Davidson, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569712/
https://www.ncbi.nlm.nih.gov/pubmed/23265842
http://dx.doi.org/10.1016/j.molmed.2012.11.003