Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ dysfunction in a rat model of acute sepsis

BACKGROUND: Sepsis-induced organ failure is the major cause of death in critical care units, and is characterized by a massive dysregulated inflammatory response and oxidative stress. We investigated the effects of treatment with antioxidants that protect mitochondria (MitoQ, MitoE, or melatonin) in...

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Detalles Bibliográficos
Autores principales: Lowes, D. A., Webster, N. R., Murphy, M. P., Galley, H. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570068/
https://www.ncbi.nlm.nih.gov/pubmed/23381720
http://dx.doi.org/10.1093/bja/aes577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570068/
https://www.ncbi.nlm.nih.gov/pubmed/23381720
http://dx.doi.org/10.1093/bja/aes577

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