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HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders

A high metabolic rate in myeloproliferative disorders is a common complication of neoplasms, but the underlying mechanisms are incompletely understood. Using three different mouse models of myeloproliferative disorders, including mice with defective cholesterol efflux pathways and two models based o...

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Detalles Bibliográficos
Autores principales: Gautier, Emmanuel L., Westerterp, Marit, Bhagwat, Neha, Cremers, Serge, Shih, Alan, Abdel-Wahab, Omar, Lütjohann, Dieter, Randolph, Gwendalyn J., Levine, Ross L., Tall, Alan R., Yvan-Charvet, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570097/
https://www.ncbi.nlm.nih.gov/pubmed/23319699
http://dx.doi.org/10.1084/jem.20121357