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MaSC: mappability-sensitive cross-correlation for estimating mean fragment length of single-end short-read sequencing data

Motivation: Reliable estimation of the mean fragment length for next-generation short-read sequencing data is an important step in next-generation sequencing analysis pipelines, most notably because of its impact on the accuracy of the enriched regions identified by peak-calling algorithms. Although...

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Detalles Bibliográficos
Autores principales: Ramachandran, Parameswaran, Palidwor, Gareth A., Porter, Christopher J., Perkins, Theodore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570216/
https://www.ncbi.nlm.nih.gov/pubmed/23300135
http://dx.doi.org/10.1093/bioinformatics/btt001