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P53, MAPK, topoisomerase II alpha and Ki67 immunohistochemical expression and KRAS/BRAF mutation in ovarian serous carcinomas

BACKGROUND: We investigated the immunohistochemical expression of p53, MAPK, topoisomerase II alpha (topoII alpha) and Ki67 in ovarian serous carcinomas (OSCs) along with mutational analysis for KRAS and BRAF. METHODS: Eighty one cases of OSCs were reviewed and examined immunohistochemically using a...

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Detalles Bibliográficos
Autores principales: Sundov, Dinka, Caric, Ana, Mrklic, Ivana, Gugic, Dijana, Capkun, Vesna, Hofman, Irena Drmic, Mise, Branka Petric, Tomic, Snjezana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570323/
https://www.ncbi.nlm.nih.gov/pubmed/23388101
http://dx.doi.org/10.1186/1746-1596-8-21