SPARC expression in CML is associated to imatinib treatment and to inhibition of leukemia cell proliferation

BACKGROUND: SPARC is a matricellular glycoprotein with growth-inhibitory and antiangiogenic activity in some cell types. The study of this protein in hematopoietic malignancies led to conflicting reports about its role as a tumor suppressor or promoter, depending on its different functions in the tu...

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Detalles Bibliográficos
Autores principales: Giallongo, Cesarina, La Cava, Piera, Tibullo, Daniele, Barbagallo, Ignazio, Parrinello, Nunziatina, Cupri, Alessandra, Stagno, Fabio, Consoli, Carla, Chiarenza, Annalisa, Palumbo, Giuseppe A, Di Raimondo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570354/
https://www.ncbi.nlm.nih.gov/pubmed/23383963
http://dx.doi.org/10.1186/1471-2407-13-60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570354/
https://www.ncbi.nlm.nih.gov/pubmed/23383963
http://dx.doi.org/10.1186/1471-2407-13-60

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