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Serum p53 antibody detection in patients with impaired lung function

BACKGROUND: TP53 gene mutations can lead to the expression of a dysfunctional protein that in turn may enable genetically unstable cells to survive and change into malignant cells. Mutant p53 accumulates early in cells and can precociously induce circulating anti-p53 antibodies (p53Abs); in fact, p5...

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Detalles Bibliográficos
Autores principales: Mattioni, Manlio, Chinzari, Patrizia, Soddu, Silvia, Strigari, Lidia, Cilenti, Vincenzo, Mastropasqua, Eliuccia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570357/
https://www.ncbi.nlm.nih.gov/pubmed/23384026
http://dx.doi.org/10.1186/1471-2407-13-62