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Evidence of reactive oxygen species-mediated damage to mitochondrial DNA in children with typical autism

BACKGROUND: The mitochondrial genome (mtDNA) is particularly susceptible to damage mediated by reactive oxygen species (ROS). Although elevated ROS production and elevated biomarkers of oxidative stress have been found in tissues from children with autism spectrum disorders, evidence for damage to m...

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Detalles Bibliográficos
Autores principales: Napoli, Eleonora, Wong, Sarah, Giulivi, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570390/
https://www.ncbi.nlm.nih.gov/pubmed/23347615
http://dx.doi.org/10.1186/2040-2392-4-2