PPARγ Activation Attenuates Glycated-Serum Induced Pancreatic Beta-Cell Dysfunction through Enhancing Pdx1 and Mafa Protein Stability

Pancreatic-duodenal homeobox-1 (Pdx1) and v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (Mafa) play important roles in sustaining the pancreatic beta-cell differentiation phenotype. Peroxisome proliferator-activated receptor-γ (PPARγ) is also a regulator of cell differentiation. Our previ...

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Detalles Bibliográficos
Autores principales: Zhu, Yunxia, Ma, Ai, Zhang, Hongxiu, Li, Chaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570423/
https://www.ncbi.nlm.nih.gov/pubmed/23424659
http://dx.doi.org/10.1371/journal.pone.0056386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570423/
https://www.ncbi.nlm.nih.gov/pubmed/23424659
http://dx.doi.org/10.1371/journal.pone.0056386

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