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Identification of CpG islands in DNA sequences using statistically optimal null filters

CpG dinucleotide clusters also referred to as CpG islands (CGIs) are usually located in the promoter regions of genes in a deoxyribonucleic acid (DNA) sequence. CGIs play a crucial role in gene expression and cell differentiation, as such, they are normally used as gene markers. The earlier CGI iden...

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Detalles Bibliográficos
Autores principales: Kakumani, Rajasekhar, Ahmad, Omair, Devabhaktuni, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570435/
https://www.ncbi.nlm.nih.gov/pubmed/22931396
http://dx.doi.org/10.1186/1687-4153-2012-12