The Evolutionary History of Amino Acid Variations Mediating Increased Resistance of S. aureus Identifies Reversion Mutations in Metabolic Regulators

The evolution of resistance in Staphylococcus aureus occurs rapidly, and in response to all known antimicrobial treatments. Numerous studies of model species describe compensatory roles of mutations in mediating competitive fitness, and there is growing evidence that these mutation types also drive...

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Detalles Bibliográficos
Autores principales: Champion, Mia D., Gray, Vanessa, Eberhard, Carl, Kumar, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570469/
https://www.ncbi.nlm.nih.gov/pubmed/23424663
http://dx.doi.org/10.1371/journal.pone.0056466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570469/
https://www.ncbi.nlm.nih.gov/pubmed/23424663
http://dx.doi.org/10.1371/journal.pone.0056466

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