Neonatal Exendin-4 Reduces Growth, Fat Deposition and Glucose Tolerance during Treatment in the Intrauterine Growth-Restricted Lamb

BACKGROUND: IUGR increases the risk of type 2 diabetes mellitus (T2DM) in later life, due to reduced insulin sensitivity and impaired adaptation of insulin secretion. In IUGR rats, development of T2DM can be prevented by neonatal administration of the GLP-1 analogue exendin-4. We therefore investiga...

Descripción completa

Detalles Bibliográficos
Autores principales: Gatford, Kathryn L., Sulaiman, Siti A., Mohammad, Saidatul N. B., De Blasio, Miles J., Harland, M. Lyn, Simmons, Rebecca A., Owens, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570470/
https://www.ncbi.nlm.nih.gov/pubmed/23424667
http://dx.doi.org/10.1371/journal.pone.0056553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570470/
https://www.ncbi.nlm.nih.gov/pubmed/23424667
http://dx.doi.org/10.1371/journal.pone.0056553

Ejemplares similares