Double restriction-enzyme digestion improves the coverage and accuracy of genome-wide CpG methylation profiling by reduced representation bisulfite sequencing

BACKGROUND: Reduced representation bisulfite sequencing (RRBS) was developed to measure DNA methylation of high-CG regions at single base-pair resolution, and has been widely used because of its minimal DNA requirements and cost efficacy; however, the CpG coverage of genomic regions is restricted an...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Junwen, Xia, Yudong, Li, Lili, Gong, Desheng, Yao, Yu, Luo, Huijuan, Lu, Hanlin, Yi, Na, Wu, Honglong, Zhang, Xiuqing, Tao, Qian, Gao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570491/
https://www.ncbi.nlm.nih.gov/pubmed/23324053
http://dx.doi.org/10.1186/1471-2164-14-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570491/
https://www.ncbi.nlm.nih.gov/pubmed/23324053
http://dx.doi.org/10.1186/1471-2164-14-11

Ejemplares similares